After the 3rd miscarriage we had blood tests done and all came back normal. Folic acid/folate and vitamin B12 are both needed in the production of red blood cells and iron utilization. A 30-year-old female asked: i take too much folic acid could i probably have a miscarriage? © 2005 - 2019 WebMD LLC. However, I had a thorough look as I wanted to know for myself and found that 2 of the three mutations I have can cause rec miscarriage and other pregnancy complications. TTC After Miscarriage. I am wondering if 5 mg is too much since I've read on places that 400 microgram is the recommended dosage. Folic acid helps make healthy red blood cells, which carry oxygen around the body. The study, published this week in the Journal of the American Medical Association, was conducted by researchers from Sweden's Karolinka Institute in conjunction with the U.S. National Institute of Child Health and Human Services (NICHD). Babies with this defect die before birth (miscarriage) or shortly after birth. In 1998, the FDA began requiring food manufacturers to fortify certain grain products with folic acid. Please let me know your opinions. You can consult a gynecologist to look for any possible causes for miscarriage. No : Low levels associated with neural tube defects and miscarriage. It is still unbelievable, as I never thought I would have another baby again, but I am confident that the influx of one of the vitamins I increased in my diet helped this baby stick.Hope everything works out for you in the future. I was put on 5mg folic acid immediately and told to take it for 1-3 months before ttc again (i took it for 2 months before my next bfp). Women with folate deficiencies were 50% more likely to experience early pregnancy losses. Dr. Sudeshan Govender answered. Animals were fed on the diets for 3 weeks. After having my daughter in 2009, I have since had 3 miscarriages and am now 7 weeks pregnant again. Investigational treatments for COVID-19. Some women will be advised to take a higher dose of 5 milligrams (5mg) of folic acid each day until they're 12 weeks pregnant if they have a higher chance of having a pregnancy affected by neural tube defects. Women who had high levels of folate in their blood were no more likely to have miscarriages than those who had lower levels. To use this feature subscribe to Mumsnet Premium - get first access to new features see fewer ads, and support Mumsnet. In this article, MomJunction tells you all about folic acid during pregnancy: how much you need, how to obtain it (sources) and when to avoid taking it. Excluded from family because we didn’t go for Xmas lunch, Long term partner’s teenage daughters completely reject me, We’re looking for parents in the North, Midlands or South East to take part in online focus groups, Find out what Mumsnet users thought of Echo by Lloyd’s Pharmacy, Talk widget showing discussions of the day & trending threads, Subscribe to Mumsnet emails direct to your inbox. The latest study was conducted in Sweden, where the grain supply is not fortified with folic acid. : Hi--just looking for some advice about supplementing with higher dose of Folic Acid: After a 'TFMR' with neural tube defects in June, my OB has put me on 5mg of Folic Acid, but strongly advised to wait until I have been on higher dose for 3 mths before trying again. Evaluation of the impact of pharmacist polypharmacy reviews within the Govan Social … It sounds like you have been through it all!A prescription for folic acid is usually given when you have tested positive for the MTHFR mutation in the standard thrombophilia work up. The new findings refute a handful of earlier studies linking high folic acid consumption to an increase in miscarriages. You may have a higher chance if: you or the baby's biological father have a neural tube defect "Almost half of the pregnancies in the U.S. are unplanned, so it is important for all women of childbearing years to get enough folic acid," she says. to prevent recurrence ; also dose recommended for women who are: receiving anti-epileptic medication (1) or ; who have diabetes (2) or; who have sickle cell disease (3) or MiL keeps taking money from DH - AIBU to say I never want to go see her again ?! I’ve heard of a lot of women being advised to take 75mg aspirin (even with no clotting disorders) and a much higher dose of folic acid but have not been advised to do anything. If you have a higher risk of having a pregnancy affected by neural tube defects you will be advised to take a higher dose of 5mg folic acid. From December to now we haven't use any contraception I was beginning to think it would never happen when I got a bfp 14/8.I started spotting on and off from 5 weeks - 6 weeks 5 days I had hcg bloods taken and scans which showed only a sac no heartbeat. You should take a 5mg folic acid supplement every day while you are trying to get pregnant, and for at least the first 12 weeks of pregnancy. This causes folate deficiency anaemia, which can cause tiredness and other symptoms. Also I'm aware I need to loose weight. Taking folic acid for at least one month before conception reduces the risk of neural-tube defects, such as spina bifida, by up to 70 percent, according to the Centers for Disease Control and Prevention. I had 4 consecutive miscarriages in a space of just over 1 year. Hi, The miscarriage was not due to Duphaston or follic acid. I just wanted to see if anyone had a successful pregnancy with either folate or 5mg folic acid ? Talk to your doctor about taking folic acid supplements to help you recover from the miscarriage. There was a story today in a UK sunday paper about a woman who had a son in 2000 and then had 18 miscarriages. Just wondering if anyone knows how much folic acid is too much? Relatively nontoxic. I am now 5 weeks into my pregnancy and have my first prenatal appt. Top Treatment Tips, The D&C (Dilation and Curettage) Procedure. These birth defects include the paralyzing spinal disease spina bifida, and anencephaly, a fatal disease in which the brain does not develop. All rights reserved. If a woman has enough folic acid in her body before and during pregnancy, her baby is less likely to have an NTD. Four groups of Wistar rats were classified on the basis of physiological status (virgin v. pregnant) and the experimental diet administered (folic-acid-supplemented, 40 mg/kg diet v. control, 2 mg folic acid/kg diet)(equivalent to 2176 mg for a 120lb woman). It is quite a common defect apparently (60% of the pop can have such a mutation) but it can cause problems in pregnancy (which is on its own a hypercoagulative condition= blood clots more in pg). Researchers compared 468 women who had miscarriages between six and 12 weeks of their pregnancies with 921 women who were also in their first trimester, but had not miscarried. After we eat folate or folic acid, the majority is converted into 5-MTHF before it enters the bloodstream, this metabolic process differs slightly between folate and folic acid. The idea behind it is that your body cannot metabolise homocysteine well - elevated levels of homocysteine are linked with neural tube defects, as well as clotting problems (and therefore miscarriage), strokes etc etc etc. Folic acid supplements, multivitamins, and prenatal vitamins usually contain the recommended minimum amount of folic acid (at least 400 micrograms). Since the FDA move, the number of children born with spina bifida in the United States has decreased by one-third, the CDC announced last month. 1st time, 3rd time, 4th, 5th, 6th and then after 10 and 1/2 years of patience I had a beautiful baby boy, 100% healthy, no mental or physical problems. 23 JUN 2020 15:13. A higher folic acid dose of 15 mg has also been used, but only for up to 60 days. Women need to take folic acid every day and Methyltetrahydrofolate reductase (MTHFR) is the enzyme that helps to turn folic acid into its active methyl-folate form. Victoria • Tue, Aug 07 • Rainbow baby due 9th oct 2019. In the latest study, women with inadequate folate levels were 50% more likely to have early pregnancy losses, but those with high folate levels did not have a greater miscarriage risk. I would also like to add to that, that high dose folic acid increases circulation in the uterus aswell, so that blood flow remains constant from the forming placenta and the hormones being released from the ovaries. "One of the easiest ways to do this is to take either a multivitamin or a folic acid or B-vitamin supplement every day if there is any chance at all of becoming pregnant.". The finding suggests that a 1998 mandate by the U.S. Food and Drug Administration to fortify grain products with folic acid (the synthetic form of the vitamin) may prevent miscarriage in some women, in addition to lowering their risk for having a child with a class of birth defects known as … Folic Acid questions? The recommended daily intake of folic acid for all women of childbearing age is at least 400 micrograms (mcg), or 0.4 milligrams (mg). Many breakfast cereals, rice, pasta, and most breads are now an excellent source of the vitamin, as are beans, leafy green vegetables, and citrus fruits. She recently gave birth to a baby girl after her Dr did a blood test and discovered that ther was virtually no folic acid in her body leading to problems when the baby`s spinal cord was being formed. I did not take any, and had 5 miscarriages. During this time I was also diagnosed with a vit D deficiency which I was treated for over a week of high dose tablets, and also started low dose aspirin from BFP. Folic acid given therapeutically enters the portal circulation largely unchanged, since it is a poor substrate for reduction by dihydrofolate reductases. Saw a haematologist two days ago who confirmed this and said that my chances of carrying a pg untreated are lower than 10%, while with treatment (injections) they can go up to 80%! Hi ladies. 800 mcg folic acid with or without 800 mg docosahexaenoic acid daily for 6 months. Third time lucky I'm going to say about 97% of people can't cook. WebMD does not provide medical advice, diagnosis or treatment. I have learned my lesson - sometimes you need to take charge of your treatment and chase dr's up - not all of them know everything. 1]) is based on a large number of women with well-documented, highly compliant use of folic acid 3 and gives us a good estimate of the rate of miscarriage among women who took folic acid. I hope I have helped a bit... Hi ju1es, I am really sorry to hear about your mc's. Folic acid in its natural form is called folate. Ju1es sorry for your losses and everything you have been through! Hey, I've had a horrendous week,I had a miscarriage on Tuesday at home.Im having an ok day today. Id been taking the normal dose of folic acid for months before and during that pregnancy. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Pregnant With Allergies? folic acid after miscarriage. Like you, all my tests came back clear for any problems. HelloI'm just going through my 5th mc in two years.After my 3rd mc this time mmc at 11 weeks last September my consultant ran all the blood tests on me and hubby (I had about 8!) Overdose associated with autism in kids . I just had my third miscarriage on Monday at 12 weeks. Folic acid is a B vitamin found in many supplements and fortified foods. I started to mc naturally last Thursday which I should have been just over 7 weeks.My consultant has now advised a prescription of 5mg folic acid and to continue taking low dose aspirin. Folic acid supplements at the time of conception helps to prevent neural tube defects. This is page 1 of 1 (This thread has 3 messages.). Let me know if I can assist you further. I've been finding it hard to get motivated with things after the miscarriage. I've read that if you have a high bmi higher than 30 you should be on a higher dose of folic acid does anyone know if this is true? It’s the synthetic form of folate.Folic acid is used by your body to make new cells and produce DNA. Folic acid is used to treat folic acid deficiency and certain types of anemia. Women who get at least 400 micrograms of the vitamin from their diets during the first few weeks of pregnancy can reduce their unborn baby's risk of neural tube defects (NTDs) by as much as 70%. But Katherine Lyon-Daniel of the CDC's folic acid education campaign tells WebMD that it is still difficult for a woman to know if she is getting enough folic acid through diet alone. I found out after my first mc that my little one had spina bifida. Ovulation Tool: Find Your Most Fertile Days. After my fourth miscarriage I was prescribed 5mg folic acid which I started taking 3 months before I conceived again. I was on folate with my first pregnancy but my doctor switched me to 5mg folic acid after my second miscarriage. Oct. 15, 2002 -- Taking folic acid before becoming pregnant is one of the best ways to prevent certain birth defects, and now research suggests it may also lower the risk of early miscarriage. Hey, Have a question about folic acid just wondered if anyone can help. But prenatal vitamins and supplements like folic acid have been shown to reduce the risk of a miscarriage and having a baby that is premature or small for its gestational age. I currently take the recommended dose as standard. Also, ask questions, youa re entitles to know! Folic acid is a vitamin used to prevent or treat a deficiency (lack of) folic acid in the body. on 17th june. What is folic acid and where can I get it? Has anybody taken this and think its helped have a healthy pregnancy and what is it meant to do?Any advice is appreciated.xx. Not sure about the whole folic acid thing. Specializes in Family Medicine. Some people need a higher dose of folic acid. Support for anyone who has had a miscarriage High dose folic acid 5mg for recurrent miscarriage. After my fourth miscarriage I was prescribed 5mg folic acid which I started taking 3 months before I conceived again. A concern of taking synthetic folic acid is that it may competitively interfere with bioactive folate, since folic acid binds more easily to receptors in your tissue. This is really important in early pregnancy, and even before conception.Although I don't have any clotting disorders, I had to personally ask for the high dose folic acid from my GP, as I had done my research into it beforehand.In saying all the above, I don't know whether it has been the low dose aspirin, the high dose folic acid or the vitamin D deficiency being treated, but something worked and I am currently 22 weeks pregnant. The dose of folic acid recommended for women hoping to conceive is: folic acid 5mg daily . megaloblastic anaemia or pernicious anaemia caused by folate and/or vitamin B12 Should I be taking 400 mcg or 800mcg I was wondering if i took more if it would help our chances since I had a miscarriage (2weeks pregnant) a few weeks ago. In the group of women with low folate levels a miscarriage was significantly more likely to occur if the fetus had an abnormal chromosome. 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