… Simparica might have the edge over Bravecto because liver flavor has been shown to be very useful with dogs. Confused about flea protection? Wash hands after using product, as it is irritating to your eyes. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Due to reduced drug bioavailability in the fasted state, fluralaner should be administered with food. The following abnormalities were noted in 7 pups from 2 of the 10 dams in only the treated group during gross necropsy examination: limb deformity (4 pups), enlarged heart (2 pups), enlarged spleen (3 pups), and cleft palate (2 pups). Palatability: In a well-controlled U.S. field study, which included 559 doses administered to 224 dogs, 80.7% of dogs voluntarily consumed Bravecto within 5 minutes, an additional 12.5% voluntarily consumed Bravecto within 5 minutes when offered with food, and 6.8% refused the dose or required forced administration. Quantifiable drug concentrations can be measured (lower than necessary for effectiveness) through 112 days. It kills and repels ticks, all life stages of fleas, and mosquitoes on contact before they bite and cause problems for your dog. Bravecto Chews is the first oral chew for dogs to provide up to 12 weeks of protection against fleas and ticks. Dosage. Peak fluralaner concentrations are achieved between 2 hours and 3 days following oral administration, and the elimination half-life ranges between 9.3 to 16.2 days. Keep the product in the original packaging until use, in order to prevent children from getting direct access to the product. There were no clinically-relevant, treatment-related effects on physical examinations, body weights, food consumption, clinical pathology (hematology, clinical chemistries, coagulation tests, and urinalysis), gross pathology, histopathology, or organ weights. Find helpful customer reviews and review ratings for Provecta Advanced For Dogs 21-55 lbs. Dermal Dose: >5,000 mg/kg in rats Orally: 450 mg/kg in rats, Imidacloprid Dermal Dose: >5,000 mg/kg in rats Imidacloprid Orally: 450 mg/kg in rats >4,000 mg/kg in rats for Permethrin, Imidacloprid Dermal Dose: >5,000 mg/kg in rats Imidacloprid Orally: 450 mg/kg in rats >2,000 mg/kg in rabbits for Moxidectin, Fipronil Dermal Dose: >5,000 mg/kg in rats Fipronil Orally: 750 mg/kg in rats; >4,000 mg/kg in rats for topical Permethrin, Fipronil Dermal Dose: >5,000 mg/kg in rats Fipronil Orally: 750 mg/kg in rats Methoprene Orally: >34,600 in rats (virtually non-toxic), Fipronil Dermal Dose: >5,000 mg/kg in rats Fipronil Orally: 750 mg/kg in rats, Indoxacarb must be activated by insect metabolism (no activity in mammals), Indoxacarb is inert in the mammal body, >4,000 mg/kg in rats for Permethrin, Dermal LD50: >2000 mg/kg (rat), Oral LD50: >2000 mg/kg (rat), approx 783 mg/kg in the rat (over 300 times the therapeutic dose in the dog), imidacloprid dermal dose: >5,000 mg/kg in ratsImidacloprid orally: 450 mg/kg in rats, flumethrin: ld50 oral rat (male) 258 mg/kg, ld50 dermal rat > 150 mg/kg, Lufenuron Orally: > 2,000 mg/kg in rats Milbemycin LD50 information unavailable Symptoms of tremors and incoordination result at 19 times recommended dose, www.comfortis4dogs.com (AcuGuard is a private label*), May promote seizures in dogs already predisposed to seizures, Puppies less than 14 weeks of age may experience a higher rate of vomiting. A single Bravecto ® Chew treatment lasts for 12 weeks in dogs, while the Spot-On lasts for 4 months for ticks and 6 months for fleas. deer tick), American dog tick, brown dog tick, and lone star tick. Provecta Advanced for Large Dogs provides your pup with 5 way protection against fleas, ticks, biting flies, mosquitoes and lice. Product doses are typically <100mg per dose. Each chew is formulated to provide a minimum dose of 11.4 mg/lb (25 mg/kg) body weight. (4 Dose) at Amazon.com. Product may be packaged in 1, 2, or 4 chews per package. We cannot confirm the completeness, accuracy and currency of the content. Provecta contains the same active ingredients as K9 Advantix II. Copyright © 2014 Intervet Inc, a subsidiary of Merck & Company Inc. PROVECTA FOR CATS. Bravecto®, has been increasing in popularity due to the convenience and efficacy of its 12-week treatments; at the same time, however, this medication is also becoming popular for its adverse side effects and alleged deaths after administering the Bravecto® flea and tick treatment. Reproductive Safety Study: Bravecto was administered orally to intact, reproductively- sound male and female Beagles at a dose of up to 168 mg/kg (equivalent to 3X the maximum label dose) on three to four occasions at 8-week intervals. I am writing for your opinion on using Bravecto, the pill that provides 12-week flea & tick protection. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Percentage of Dogs with Adverse Reactions in the Field Study, Bravecto Group: Percentage of Dogs with the AR During the 182-Day Study (n=224 dogs), Active Control Group: Percentage of Dogs with the AR During the 84-Day Study (n=70 dogs). Bravecto is a chewable, pork-flavored tablet for dogs. In a well-controlled laboratory study, Bravecto demonstrated 100% effectiveness against adult fleas 48 hours post-infestation for 12 weeks. 7 weeks puppies 8 weeks kittens. You can administer Bravecto any time, day or night, but it’s best to give him the pork-flavored tablet around feeding time. Bravecto Chew for Dogs is approved for use in breeding, pregnant, and lactating dogs. Imidacloprid & Permethrin. Other Parasites Killed, Controlled or Repelled, Manufacturer recommends against use but not specifically labeled against, Hookworms, Roundworms, Whipworms & Heartworm, Manufacturer recommends consulting with veterinarian first, Begins Killing Fleas in 4 hours,99% Fleas Dead within 8 hours, Demodectic Mange Mites, Ticks, Sarcoptic Mange Mites, Dogs: Ticks, Ear Mites, Sarcoptic Mange Mites & Heartworm LarvaeCats: Hookworms, Roundworms, Ear Mites & Heartworm Larvae, Greater than 98% of Pre-Existing Fleas Dead within 24 Hours; Then New Fleas Greater than 93.8% within 12 hours, Ticks, Hookworms, Roundworms, Ear Mites, Heartworm, 98% of Pre-Existing Fleas Dead in 12 Hours; Then New Fleas in 2 Hours, Dogs: Whipworms, Hookworms, Roundworms & Heartworm Cats: Hookworms, Roundworms, Ear Mites & Heartworm, daily or as needed (but not more than once a day), 90% of fleas dead in 6 hours, 99% in 12 hours, Frontline, Fiproguard, PetArmor EasySpot (cats) Parastar (dogs) Effipro (cats), 24 Hrs to Translocate, then 4-18 Hours to Kill Fleas, 24 Hrs to Translocate, then 4-18 Hrs to Kill Fleas and 24-48 Hours to Kill Ticks, 99.9% of fleas dead in 72 hours (66% of fleas dead in 24 hours), Ticks, Sarcoptic Mange Mites, Demodectic Mange mites, 12 Weeks(only kills Lone Star ticks for 8 weeks), every 12 weeks for fleas(every 8 weeks for ticks), >96.2% of fleas dead within 8 hours, begins to kills fleas after 3 hours, 24 hours (after that new fleas killed within 2 hours), Ticks, Lice, aids in Sarcoptic Mange control, 8 months (5 months if pet swimsor bathes once a month or more),30 days for lice, Monthly for oral; Every 6 Months for Injectable, Individual ingredients Yes, but combination not approved, Prescription Drug, Non-Prescription Drug or Insectcide, Lethal Dose to 50% of the Population(the higher the number, the safer the product)[What is LD50? Five of the twelve treated dogs that experienced one or more of these signs did so within 6 hours of the first dosing. TRUSTED PROTECTION. One dog in the 3X treatment group was observed to be dull, inappetant, with evidence of bloody diarrhea, vomiting, and weight loss beginning five days after the first treatment. There are no known contraindications for the use of the product. Fleas tend to get more active when this product works on them so tend to be more visible. Hello. Bravecto is also indicated for the treatment and control of Amblyomma americanum (lone star tick) infestations for 8 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater. Provecta Advanced for Dogs is a once-a-month topical prevention and treatment for dogs seven weeks and older that contains the same active ingredients as K9 Advantix II. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 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